翻訳と辞書 Words near each other ・ Paradox vole ・ Paradox, Colorado ・ Paradoxa ・ Paradoxa (fungus) ・ Paradoxa Paradoxa ・ Paradoxa Stoicorum ・ Paradoxa thomensis ・ Paradoxecia ・ Paradoxes of material implication ・ Paradoxes of set theory ・ Paradoxia ・ Paradoxica ・ Paradoxica asymmetrica ・ Paradoxica parki ・ Paradoxica proxima ・ Paradoxical disinhibition ・ Paradoxical embolism ・ Paradoxical Frog (album) ・ Paradoxical intention ・ Paradoxical laughter ・ Paradoxical reaction ・ Paradoxical set ・ Paradoxiconus ・ Paradoxides ・ Paradoxides bohemicus ・ Paradoxides davidis ・ Paradoxididae ・ Paradoxidoidea ・ Paradoxodacna piratica ・ Paradoxodes Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Paradoxical disinhibition ： ウィキペディア英語版 Paradoxical disinhibition Paradoxical disinhibition is a paradoxical reaction, an uncommon but recognized phenomenon, characterized by acute excitement and an altered mental state, caused by benzodiazepines, the mechanism being poorly known, but the most accepted theory is that it occur secondary to inhibition of the restraining influences of the cortex and frontal lobe due to the GABA-mimetic action of benzodiazepines.〔http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2047018/pdf/bjpg57-407.pdf〕 Reversal of this action, could be attained by an NMDA-receptor antagonist - ketamine.〔http://utenti.unife.it/giampaolo.garani/Sedazione-Farmaci/midazolam%20premedication%20in%20pediatric%20patients.pdf〕 ==Mechanism== It is thought that blockage of presynasptic GABA receptors of GABAergic neurons induce stimulation as a net effect, because the action of the most powerful inhibitory neurotransmitter, GABA, is blocked.〔Kaplan Step 1 2010 Video, Pharmacology, Sec04.Ch01A, Sedative.Hypnotic.Anxiolytic.Drugs〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Paradoxical disinhibition」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.